The AmCham MENA Regional Council (MENA Council) was established in 2005, and comprises the AmChams of Abu Dhabi-UAE, Algeria, Bahrain, Egypt, Jordan, Lebanon, Morocco, Palestine and Tunisia. The objective of the Council is to foster increased collaboration and cooperation amongst the members, and to work on

The Council works on effectively linking the various members, and institutionalizing their ongoing coordination with the U.S. Chamber of Commerce. It also works on promoting Free trade agreements (FTAs) between MENA countries and the U.S., and on fostering increased awareness among MENA region manufacturers and producers of export opportunities to the U.S. through those agreements.

AmCham Tunis is the current chair of the Council, and AmCham Abu Dhabi is the Vice Chair. The Council's permanent secretariat resides at AmCham Egypt.